Molecular Formula | C20H17FN6O |
Molar Mass | 376.39 |
Density | 1.47±0.1 g/cm3(Predicted) |
pKa | 2.70±0.12(Predicted) |
Storage Condition | Room Temprature |
biological activity | MAK683 (EED inhibitor-1, example 2) is an inhibitor of embryonic ectoderm development (EED). The corresponding IC50 values of MAK683 in EED Alphascreen binding, LC-MS and ELISA analysis are 59 nM, 89 nM and 26 nM respectively. |
target | TargetValue EED (ELISA say) 26 nM EED (EED Alphascreen binding say) 59 nM EED (LC-MS say) 89 nM |
Target | Value |
EED (ELISA assay) | 26 nM |
EED (EED Alphascreen binding assay) | 59 nM |
EED (LC-MS assay) | 89 nM |